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End Point Prediction: Gran Plot01:07

End Point Prediction: Gran Plot

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A Gran plot is used to predict the equivalence volume or endpoint of a potentiometric or acid-base titration without reaching the endpoint. Typically, titration data is collected as a function of the titrant's volume up to a point less than the equivalence volume and then transformed into a linear format. The straight line is extended to the x-axis, indicating the necessary titrant volume to achieve the equivalence point.
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Managing signal sampling rates is essential in digital signal processing to maintain signal integrity. A decimated signal, characterized by a reduced frequency range due to its lower sampling rate, can be upsampled by inserting zeros between each sample. This upsampling process expands the original spectrum and introduces repeated spectral replicas at intervals dictated by the new Nyquist frequency. To refine this zero-inserted sequence, it is passed through a lowpass filter with a cutoff...
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When considering a sampled sequence with zero values between sampling instants, one can replace it by taking every N-th value of the sequence. At these integer multiples of N, the original and sampled sequences coincide. This process, known as decimation, involves extracting every N-th sample from a sequence, thereby creating a more efficient sequence.
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Sampling materials are classified into three main types: solid, liquid, and gas.
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Updated: Sep 9, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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Scalable and effective negative sample generation for hyperedge prediction.

Shilin Qu1, Weiqing Wang1, Yuan-Fang Li1

  • 1Monash University, Wellington Rd, Melbourne, 3800, Australia.

Neural Networks : the Official Journal of the International Neural Network Society
|August 31, 2025
PubMed
Summary
This summary is machine-generated.

We introduce SEHP, a novel method for generating negative hyperedges in hypergraph analysis. SEHP overcomes scalability issues and improves prediction accuracy by using conditional diffusion models for hyperedge prediction.

Keywords:
Conditional diffusionHyperedge predictionHypergraph representationNegative sample generation

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Area of Science:

  • Complex Systems Analysis
  • Network Science
  • Machine Learning

Background:

  • Hypergraphs excel at modeling complex systems by capturing multi-entity interactions, outperforming traditional graphs.
  • Hyperedge prediction is crucial for analyzing hypergraphs, requiring effective negative hyperedge sampling for model training.
  • Existing negative sampling methods lack generalizability and scalability, especially for large hypergraphs.

Purpose of the Study:

  • To develop a scalable and effective method for generating informative negative hyperedges for hyperedge prediction.
  • To adapt diffusion models for the discrete space of negative hyperedge generation in hypergraphs.
  • To improve the accuracy and scalability of hyperedge prediction models.

Main Methods:

  • Introduced SEHP (Scalable and Effective Negative Sample Generation for Hyperedge Prediction), a conditional diffusion model for iterative negative hyperedge generation and refinement.
  • Developed sub-hypergraph sampling techniques to integrate global structural information for scalable batch training.
  • Addressed the challenges of applying diffusion models to discrete negative sample generation.

Main Results:

  • SEHP effectively generates and refines negative hyperedges, pushing them towards the decision boundary to enhance model performance.
  • The method demonstrates superior scalability by enabling batch training on sampled sub-hypergraphs.
  • Extensive experiments on real-world datasets show SEHP outperforming state-of-the-art methods in prediction accuracy and scalability.

Conclusions:

  • SEHP offers a significant advancement in negative hyperedge generation for hypergraph analysis.
  • The proposed conditional diffusion model approach is effective and scalable for large hypergraphs.
  • SEHP improves hyperedge prediction performance and addresses limitations of existing methods.