Cognitive discrepancy patterns and their association with psychosocial functioning across affective disorders.
Muriel Vicent-Gil1, Maria Serra-Blasco2, Joan Trujols1
1Sant Pau Mental Health Group, Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain; Hospital de la Sant Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain; CIBER de Salud Mental, Instituto de Salud Carlos III, Madrid, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.
Major depressive disorder patients often underestimate their cognitive abilities, while bipolar disorder patients tend to overestimate theirs. Accurate cognitive assessment is crucial for effective treatment in affective disorders.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Major depressive disorder (MDD) and bipolar disorder (BD) patients often show discrepancies between self-reported and objectively measured cognition.
- These cognitive discrepancies may differ between disorders and are influenced by clinical and sociodemographic factors.
- Understanding these discrepancies is vital as overestimation is linked to better functioning in depression, while underestimation correlates with worse functioning.
Purpose of the Study:
- To investigate cognitive discrepancies in patients with MDD and BD compared to healthy controls.
- To identify factors associated with cognitive under- or overestimation.
- To examine the impact of diagnosis and cognitive discrepancy patterns on psychosocial functioning.
Main Methods:
- A cross-sectional study involving 200 participants (160 patients with MDD or BD in remission, 40 healthy controls).
- Collection of sociodemographic, clinical, and functional data alongside subjective and objective cognitive measures.
- Multivariate logistic regression and two-way ANOVA were used to analyze cognitive discrepancies and their effect on functioning.
Main Results:
- Patients with MDD tended to underestimate cognitive abilities, whereas BD patients tended to overestimate them.
- Higher depressive symptoms and intellectual level were associated with reporting more subjective cognitive disturbances.
- Worse psychosocial functioning was linked to the diagnosis itself, particularly in bipolar disorder, rather than cognitive underestimation.
Conclusions:
- Cognitive assessment in affective disorders requires personalized approaches integrating both subjective and objective measures.
- Avoiding generalizations is essential for accurate evaluation of cognitive symptoms.
- Tailored cognitive evaluations can improve understanding and management of cognitive deficits in MDD and BD.
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