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Canadian perinatal opioid project: a protocol for a national health data system.

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This study establishes a Canadian data system to track opioid use during pregnancy and its effects on maternal and child health. Findings will inform better support for families affected by perinatal opioid exposure.

Keywords:
Community child healthEPIDEMIOLOGYOBSTETRICSPUBLIC HEALTHPostpartum PeriodPrescriptions

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Area of Science:

  • Public Health
  • Epidemiology
  • Health Data Science

Background:

  • Opioid use during pregnancy poses risks to parents and children, yet long-term health effects in Canada remain understudied.
  • There is a critical need for evidence to guide optimal support for maternal and child health following perinatal opioid exposure.

Purpose of the Study:

  • To develop the Canadian Perinatal Opioid Project, a national data system for tracking perinatal opioid exposures.
  • To link these exposures with subsequent maternal and child health outcomes across Canada.

Main Methods:

  • Utilizing population-based administrative health records from five Canadian provinces (Alberta, British Columbia, Manitoba, Ontario, Saskatchewan) from 2013-2023.
  • Establishing cohorts of pregnancies and liveborn infants, with follow-up periods of 1 year for parents and 8 years for infants.
  • Integrating data from prescription records, hospitalizations, emergency visits, physician visits, birth registries, and vital statistics.

Main Results:

  • Descriptive statistics will characterize incidence and cohort features.
  • Poisson regression will analyze annual trends in perinatal opioid exposure and outcomes.
  • Patient-level analyses within provinces will be aggregated and meta-analyzed for national insights.

Conclusions:

  • The Canadian Perinatal Opioid Project will provide crucial data on the health impacts of perinatal opioid exposure.
  • Findings will inform public health policies and interventions to improve care for affected families.
  • Dissemination through publications, conferences, and an open-access dashboard will ensure broad accessibility of research findings.