Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Investigation of bioimpedance as a method for wearable noninvasive bladder volume measurements in individuals with spinal cord injury or disease: protocol of a feasibility study.

Frontiers in urology·2026
Same author

Precision Rehabilitation in Spinal Cord Injury: A Systematic Review of Omics Applications for Intervention Monitoring in Spinal Cord Injury.

Archives of rehabilitation research and clinical translation·2026
Same author

Survey on the acceptability of digital impression procedures in care-dependent older adults in Zurich: an exploratory study.

Journal of dentistry·2026
Same author

A Chromatographic Test Reveals Homeopathic Preparations Affect Human Blood In Vitro.

Homeopathy : the journal of the Faculty of Homeopathy·2026
Same author

Morpho-Anatomical and HPTLC Investigations of Lysimachia nummularia L. (Primulaceae) Grown in Switzerland.

Microscopy research and technique·2026
Same author

Contiguous temporal withholding for hemispheric analysis in frontal EEG during cycling.

MethodsX·2026
Same journal

Proteomics in Acute Myeloid Leukemia: Current Applications in Precision Medicine and Targeted Immunotherapy.

Technology in cancer research & treatment·2026
Same journal

EML4-ALK in Non-small Cell Lung Cancer: Molecular Mechanisms and Targeted Therapies.

Technology in cancer research & treatment·2026
Same journal

Developing and Validating a Risk Model for Severe Bone Marrow Suppression in Esophageal Cancer Treated with Radiotherapy or Chemoradiotherapy: A Retrospective Cohort Study.

Technology in cancer research & treatment·2026
Same journal

A Novel Adjustable Tandem and Ring Applicator for Improved Dosimetry in Cervical Cancer HDR Brachytherapy.

Technology in cancer research & treatment·2026
Same journal

Construction and Clinical Validation of a Colorectal Cancer OPISV Prognostic Model Integrating EPHB2 and ZNF346: Potential Regulatory Role of the Axon Guidance Pathway.

Technology in cancer research & treatment·2026
Same journal

Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Melanoma: A Systematic Review of Phase One Clinical Trials.

Technology in cancer research & treatment·2026
See all related articles

Related Experiment Video

Updated: Sep 9, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
06:53

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

8.8K

Multi-cancer Detection Using Pattern Formation in Drying Body Fluids: A Systematic Review and Meta-Analysis of

Maria Olga Kokornaczyk1,2, Marcus Reif3, Martin Loef3,4

  • 1Society for Cancer Research, Arlesheim, Switzerland.

Technology in Cancer Research & Treatment
|September 1, 2025
PubMed
Summary
This summary is machine-generated.

Diagnostic patterning tests (DPTs) show high accuracy for detecting over 50 cancer types. These novel fluid-patterning methods offer potential for earlier cancer diagnosis and improved patient outcomes.

Keywords:
copper chloride crystallization of blooddiagnostic testsdroplet evaporationmeta-analysismulti-cancer detectionpatterns in drying body fluids

More Related Videos

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers
08:44

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers

Published on: June 11, 2018

10.6K
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.8K

Related Experiment Videos

Last Updated: Sep 9, 2025

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids
06:53

Detection and Monitoring of Tumor Associated Circulating DNA in Patient Biofluids

Published on: June 8, 2019

8.8K
Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers
08:44

Dried Blood and Serum Spots As A Useful Tool for Sample Storage to Evaluate Cancer Biomarkers

Published on: June 11, 2018

10.6K
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.8K

Area of Science:

  • Oncology
  • Biophysics
  • Diagnostic Medicine

Background:

  • Early cancer detection is crucial for improving treatment outcomes and reducing mortality.
  • Diagnostic patterning tests (DPTs), analyzing self-organized patterns in drying body fluids, represent an emerging diagnostic modality.
  • The accuracy of DPTs for multi-cancer detection remains underexplored.

Purpose of the Study:

  • To systematically review and meta-analyze the diagnostic accuracy of DPTs for multi-cancer detection.
  • To assess the performance of DPTs across various cancer types, stages, and control groups.

Main Methods:

  • Systematic literature search across multiple databases (PubMed, Web of Science, eLibrary Russia).
  • Inclusion of 41 studies with 15,969 participants (5265 cancer cases, 189 precancerous cases).
  • Quality assessment using QUADAS-2 tool and meta-analysis following Cochrane Handbook guidelines.

Main Results:

  • Pooled sensitivity of DPTs was 0.89 (95% CI, 0.83-0.93) and pooled specificity was 0.90 (95% CI, 0.84-0.93).
  • Copper chloride crystallization in blood showed high sensitivity (0.93) and specificity (0.93).
  • DPTs demonstrated satisfactory accuracy in detecting over 50 cancer types, despite study heterogeneity.

Conclusions:

  • Diagnostic patterning tests exhibit promising accuracy for detecting a wide range of cancers.
  • Further research is warranted to validate DPTs for early cancer detection applications.
  • DPTs hold potential as a non-invasive tool to aid in cancer diagnostics.