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Chronic prostatitis: comments on infectious etiologies and antimicrobial treatment
The Prostate
|January 1, 1985
Summary
Bacterial prostatitis is rarely identified by standard cultures, with most cases (83%) lacking a clear microbial cause. Current antibiotic treatments show limited effectiveness, necessitating broader research into chronic prostatitis etiology.
Area of Science:
- Urology
- Microbiology
Background:
- Chronic prostatitis affects numerous males, often with an unknown cause.
- Bacterial infections are suspected but frequently unconfirmed.
Purpose of the Study:
- To investigate the bacterial etiology of chronic prostatitis.
- To evaluate the efficacy of cefadroxil and oral carbenicillin in treating chronic prostatitis.
Main Methods:
- Utilized the Stamey and Meares method for bacterial evaluation in 23 males.
- Administered cefadroxil or oral carbenicillin to 16 patients.
Main Results:
- Only 17% of patients had bacterial prostatitis identified via culture.
- Coagulase-negative Staphylococcus, Enterobacter agglomerans, and Haemophilus parainfluenzae were identified.
- Symptomatic relief was reported by 57% on carbenicillin and 33% on cefadroxil.
Conclusions:
- A common bacterial etiology for chronic prostatitis was not identified.
- Routine bacteriologic culture failed to identify the cause in 83% of cases.
- Further research is needed to explore novel etiologic agents and treatments for chronic prostatitis.