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Managing Perforating Internal Root Resorption in Mature Incisor with Laser-assisted Regenerative Endodontic
Guoying Lu1, Xiuqing Wang1, Ruonan Chen1
1Fujian Key Laboratory of Oral Diseases & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatology Key Lab of Fujian College and University & Institute of Stomatology & Research Center of Dental and Craniofacial Implants, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China; Clinical Research Center for Oral Tissue Deficiency Diseases of Fujian Province, School and Hospital of Stomatology, Fujian Medical University, Fuzhou, China.
Laser-assisted regenerative endodontic procedures (REPs) successfully treated perforating internal root resorption (PIRR) in a mature tooth. This innovative approach promoted healing and hard tissue formation over three years.
Area of Science:
- Endodontics
- Regenerative Dentistry
- Dental Trauma Management
Background:
- Perforating internal root resorption (PIRR) poses a significant challenge in endodontic treatment.
- Mature teeth with PIRR often present complex clinical scenarios requiring advanced therapeutic strategies.
Purpose of the Study:
- To evaluate the efficacy of laser-assisted regenerative endodontic procedures (REPs) for managing PIRR in a mature incisor.
- To assess the long-term outcomes of this novel treatment approach.
Main Methods:
- A case report detailing the treatment of a 24-year-old female with PIRR in a maxillary anterior tooth.
- Utilized cone-beam computed tomography (CBCT) for diagnosis and treatment planning.
- Performed a novel laser-assisted REPs to address the PIRR and associated inflammatory lesion.
Main Results:
- Three-year follow-up demonstrated complete apical healing.
- Cessation of root resorption was observed.
- Significant hard tissue formation within the resorptive defect was evident.
Conclusions:
- Laser-assisted REPs proved effective in managing infection and promoting healing in a mature tooth with PIRR.
- The unique vascularization through lateral perforations enhanced the regenerative potential of REPs.
- This case highlights a promising therapeutic option for complex endodontic resorption defects.

