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Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain
Published on: August 8, 2019
Identifying early risk factors for chronic pain development following vertebral fractures: a single-center
Yutaro Kondo1, Hideki Kataoka2,3, Kyo Goto2,3
1Department of Rehabilitation, Kyushu Rosai Hospital Moji Medical Center, Fukuoka, Japan.
Study Design:
Longitudinal cohort study.
Purpose:
To investigate factors associated with chronic pain (CP) development following vertebral fracture (VF).
Overview Of Literature:
Factors contributing to CP development after VFs are not well characterized.
Methods:
Hospitalized patients with acute VFs underwent assessment of vertebral morphology and paraspinal muscles. Two weeks post-admission, patients were evaluated for pain intensity (using the Verbal Rating Scale [VRS]), pain sensitivity (Pressure Pain Threshold [PPT] and Conditioned Pain Modulation), psychological factors, physical function, and activity levels. At 12 weeks, patients were categorized into CP and non-CP (NCP) groups based on VRS scores. Between-group comparisons and logistic regression analysis were performed to identify predictors of CP development.
Results:
The CP group exhibited significantly lower remote PPT and reduced low-intensity physical activity time, but higher Pain Catastrophizing Scale rumination scores and prolonged 5-Times Sit-to-Stand Test (5SST) compared to the NCP group. Logistic regression identified prolonged 5SST and reduced low-intensity physical activity as independent predictors of CP development.
Conclusions:
Prolonged 5SST and reduced low-intensity physical activity may predict CP development after VFs. Early assessment of these factors may facilitate CP risk screening in hospitalized patients with VFs.
