Octahedral Cs₂AgBiBr₆ Double Perovskite Microcrystals for C-C Coupling Reactions under Visible-Light Irradiation

Area of Science:

• Materials Science
• Catalysis
• Organic Chemistry

Background:

• Traditional C-C coupling reactions often rely on toxic or expensive catalysts.
• Developing sustainable and efficient catalytic systems is crucial for green chemistry.

Purpose of the Study:

• To investigate the application of lead-free double perovskite microcrystals (Cs₂AgBiBr₆ MCs) as catalysts in sustainable C-C coupling reactions.
• To evaluate the catalytic activity, selectivity, and scalability of Cs₂AgBiBr₆ MCs.

Main Methods:

• Synthesis and characterization of lead-free double perovskite microcrystals (Cs₂AgBiBr₆ MCs).
• Application of Cs₂AgBiBr₆ MCs as a catalyst in the α-alkylation of aldehyde and 2-bromoacetophenone.
• Validation of the catalytic system using a continuous-flow reactor for gram-scale synthesis.

Main Results:

• Cs₂AgBiBr₆ MCs demonstrated ultrahigh activity and selectivity in C-C coupling reactions.
• Achieved record-breaking reaction rates (2687.5 mmolg^-1h^-1), turnover numbers (TON, 22854.5), and turnover frequencies (TOF, 2856.8 h^-1).
• Gram-scale synthesis yielded 86% product in a continuous-flow system, proving scalability.

Conclusions:

• Cs₂AgBiBr₆ MCs represent a highly effective and environmentally compatible catalyst for solar-driven C-C bond formation.
• This work establishes a promising new platform for sustainable organic transformations using perovskite-based materials.