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mtrk-A flexible environment for developing open-source MRI pulse sequences.

Anais Artiges1,2, Amanpreet Singh Saimbhi1,2, Carlos Castillo-Passi3,4,5

  • 1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York.

Magnetic Resonance in Medicine
|September 2, 2025
PubMed
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This summary is machine-generated.

mtrk is a new open-source tool simplifying magnetic resonance imaging (MRI) pulse sequence design and implementation. It enables users to create and simulate sequences easily, achieving high similarity to vendor sequences.

Area of Science:

  • Medical Imaging
  • Software Engineering
  • Magnetic Resonance Imaging

Background:

  • Designing and implementing MRI pulse sequences is complex and time-consuming.
  • Current methods often lack flexibility and user-friendliness, hindering rapid development and dissemination.

Purpose of the Study:

  • Introduce mtrk, an open-source framework for simplified MRI pulse sequence design, implementation, and sharing.
  • Leverage modern software engineering principles for a vendor-agnostic and accessible tool.

Main Methods:

  • Developed mtrk with a human-readable descriptive language and both Python and graphical interfaces.
  • Enabled pulse sequence diagram visualization and scanner execution via a driver sequence.
  • Designed a spin-echo sequence using mtrk, converted it to Pulseq, and compared it with vendor sequences in phantom and in vivo experiments.
Keywords:
MRI pulse sequencesPulseqmtrkopen‐source software

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Main Results:

  • mtrk and Pulseq generated nearly identical images, showing over 90% similarity to vendor sequences.
  • Phantom images from mtrk sequences closely matched simulated synthetic images.
  • The graphical interface allowed design and simulation without programming expertise.

Conclusions:

  • mtrk simplifies MRI pulse sequence development through an intuitive language and Pulseq compatibility.
  • The tool facilitates accessible design and simulation, even for users without programming experience.
  • mtrk promotes efficient pulse sequence creation and sharing in the MRI community.