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Multimodality Imaging of Left Coronary Artery Complete Occlusion With Thrombosis Secondary to Kawasaki Disease

Minjie Wan1, Wei Li1, Fengjuan Yao1

  • 1Department of Medical Ultrasonics, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

Echocardiography (Mount Kisco, N.Y.)
|September 2, 2025
PubMed

Insights

Kawasaki disease (KD) can cause rare giant coronary artery aneurysms. This case highlights KD leading to complete left coronary artery occlusion and thrombus, a significant finding in pediatric cardiology.

Area of Science:

  • Pediatric Cardiology
  • Rheumatology
  • Vascular Biology

Background:

  • Kawasaki disease (KD) is a leading cause of acquired heart disease in children.
  • Giant coronary artery aneurysms (GCAAs) are infrequent but serious complications of KD.
  • GCAAs pose risks of thrombosis, stenosis, and myocardial infarction.

Observation:

  • This report details a rare case of GCAAs secondary to KD.
  • The patient presented with complete occlusion of the entire left coronary artery.
  • Evidence of extensive thrombus formation within the occluded artery was observed.

Findings:

  • Kawasaki disease can lead to complete occlusion of the left coronary artery.
  • Thrombus formation in the entire left coronary artery is a potential complication of KD-induced GCAAs.
  • This represents the first documented instance of such extensive coronary artery involvement.

Implications:

  • Highlights the potential for severe coronary complications in KD patients.
  • Emphasizes the need for vigilant monitoring and early intervention in KD.
  • Informs clinical management strategies for pediatric patients with complex coronary artery aneurysms.

Keywords:
Kawasaki diseasecoronary artery occlusionechocardiography

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