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Immunotherapy Resistance in Lethal Prepubescent Spitz Melanoma With TERT Promoter Variant

Alissa Groisser1, Liny John1, A Yasmine Kirkorian2

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JCO Precision Oncology
|September 2, 2025
PubMed
Summary

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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