Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.5K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.5K
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.2K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.2K
2D NMR: Overview of Homonuclear Correlation Techniques01:16

2D NMR: Overview of Homonuclear Correlation Techniques

290
Homonuclear correlation spectroscopy (COSY) is a powerful technique used in Nuclear Magnetic Resonance (NMR) spectroscopy to study the correlations between nuclei of the same type within a molecule. It provides information about scalar couplings between adjacent nuclei, which helps determine connectivity and structural information. There are several COSY variants, each with its unique strengths and experimental parameters.
COSY90 is the standard two-dimensional (2D) COSY experiment that...
290

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A springback TV algorithm for image reconstruction from sparse view data in CT.

Physics in medicine and biology·2025
Same author

A novel high order directional total variation algorithm of EPR imaging for fast scan.

Journal of X-ray science and technology·2025
Same author

A directional relative TV algorithm for sparse-view CT reconstruction.

Journal of X-ray science and technology·2025
Same author

Cpi-awHOTV: A CAD prior improved adaptive-weighted high order TV algorithm for orthogonal translation CL.

Journal of X-ray science and technology·2025
Same author

MAFA-Uformer: Multi-attention and dual-branch feature aggregation U-shaped transformer for sparse-view CT reconstruction.

Journal of X-ray science and technology·2025
Same author

Directional TV algorithm for image reconstruction from sparse-view projections in EPR imaging.

Physics in medicine and biology·2024

Related Experiment Video

Updated: Sep 9, 2025

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
10:00

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles

Published on: July 5, 2016

11.9K

HDTV: a high-order directional total variation reconstruction algorithm from sparse and limited-angle data in

Yanjun Zhang1, Peng Liu1,2, Chenyun Fang1

  • 1School of Computer and Information Technology, Shanxi University, Taiyuan, China.

Quantitative Imaging in Medicine and Surgery
|September 2, 2025
PubMed
Summary

This study introduces a novel high-order directional total variation (HDTV) method to accelerate electron paramagnetic resonance imaging (EPRI) scanning. The HDTV-CP algorithm significantly reduces scanning time and artifacts, improving image quality for adaptive radiation therapy.

Keywords:
Electron paramagnetic resonance imaging (EPRI)directional total variation (DTV)high-orderlimited-angle reconstructionsparse reconstruction

More Related Videos

Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

7.6K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.7K

Related Experiment Videos

Last Updated: Sep 9, 2025

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
10:00

Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles

Published on: July 5, 2016

11.9K
Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

7.6K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

19.7K

Area of Science:

  • Medical Imaging
  • Computational Imaging
  • Biomedical Engineering

Background:

  • Electron paramagnetic resonance imaging (EPRI) is crucial for adaptive radiation therapy, but long scanning times hinder its clinical application.
  • Reducing EPRI scanning time is essential for widespread adoption and improved tumor control.
  • Sparse reconstruction and limited-angle data acquisition are key strategies to accelerate EPRI.

Purpose of the Study:

  • To develop a novel method for accelerating three-dimensional (3D) EPRI by combining sparse and limited-angle data acquisition.
  • To improve the precision and imaging quality of accelerated EPRI.
  • To address the limitations of existing EPRI scanning times.

Main Methods:

  • Proposed a high-order directional total variation (HDTV) model with high-order constraints to suppress staircase artifacts.
  • Derived the Chambolle-Pock (CP) algorithm for solving the HDTV model.
  • Implemented sparse acquisition using limited-angle data for accelerated 3D EPRI.

Main Results:

  • The HDTV-CP algorithm effectively suppresses artifacts from limited-angle and sparse data, preserving image details.
  • Validated on simulation and real data, demonstrating superior performance over classic total variation (TV) methods.
  • Achieved a significant reduction in normalized root mean square error (nRMSE) from 0.34 to 0.16 and an increase in Pearson correlation coefficient (PCC) from 0.93 to 0.98.

Conclusions:

  • Successfully combined limited-angle and sparse reconstruction challenges in EPRI for the first time.
  • The HDTV method offers potential for up to 16x acceleration in EPRI imaging without compromising quality in specific scenarios.
  • The developed techniques have potential applications in limited-angle computed tomography (CT) image reconstruction.