Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Vomiting01:22

Pathophysiology of Vomiting

4.6K
Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
4.6K
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.9K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.9K
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

982
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
982
Peptic Ulcer01:27

Peptic Ulcer

53
Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
53
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

89
The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
89
Peptic Ulcer Disease II: Pathophysiology01:24

Peptic Ulcer Disease II: Pathophysiology

77
Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
77

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DiaBetter Together: Outcomes of a Randomized Controlled Trial Evaluating a Peer Mentor Behavioral Intervention for Young Adults With Type 1 Diabetes During the Transfer From Pediatric to Adult Care.

Diabetes care·2026
Same author

Lean on me: Social factors and diabetes outcomes among young adults with type 1 diabetes prior to transitioning to adult care.

Diabetic medicine : a journal of the British Diabetic Association·2026
Same author

Characterizing CSF inflammatory proteomics in pediatric post-hemorrhagic hydrocephalus and Anti-NMDAR encephalitis.

Journal of neuroinflammation·2025
Same author

Monogenic Mimics of Neuroinflammatory Phenotypes in Children and Young Adults: An Evolving Landscape.

Neurology. Genetics·2025
Same author

Clinician, Youth, and Parent Perspectives on Diabetes Technology Education.

The science of diabetes self-management and care·2025
Same author

Significance of brain lesions associated with optic neuritis in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease.

Multiple sclerosis and related disorders·2025

Related Experiment Video

Updated: May 6, 2026

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

5.8K

Associations between executive functioning and adherence in pediatric celiac disease.

Maegan D Sady1, Shayna S Coburn2,3, Zachary Kramer2

  • 1(current institution) Psychological Assessment Resources, Inc.

Children'S Health Care : Journal of the Association for the Care of Children'S Health
|September 2, 2025
PubMed
Summary

Children with celiac disease (CD) need a strict gluten-free diet. This study found that executive functioning (EF) challenges, like behavioral and cognitive regulation issues, are linked to lower dietary adherence in youth with CD.

Keywords:
ADHDadherenceattentionceliac diseaseexecutive functioning

More Related Videos

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

8.5K
Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

15.9K

Related Experiment Videos

Last Updated: May 6, 2026

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

5.8K
Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
12:55

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties

Published on: September 27, 2020

8.5K
Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

15.9K

Area of Science:

  • Pediatric Gastroenterology
  • Neuropsychology
  • Adolescent Health

Background:

  • Celiac disease (CD) requires a strict gluten-free diet for management.
  • Dietary adherence in children with CD can be challenging.
  • Executive functioning (EF) and attention may influence adherence.

Purpose of the Study:

  • To investigate the association between attention, EF, and dietary adherence in children with CD.
  • To identify specific EF domains impacting adherence.
  • To explore age-related differences in this association.

Main Methods:

  • Parental ratings of attention, EF, and dietary adherence were collected.
  • 34 children diagnosed with CD participated.
  • Correlational analyses and regression models were used.

Main Results:

  • Lower adherence was significantly correlated with poorer behavioral and cognitive regulation.
  • An interaction effect indicated that age moderated the relationship between behavioral regulation and adherence.
  • Adolescents with lower adherence showed more behavioral regulation difficulties.

Conclusions:

  • Executive functioning deficits, particularly in behavioral and cognitive regulation, are associated with lower gluten-free diet adherence in youth with CD.
  • These EF challenges are a critical consideration for treatment, especially in adolescents.
  • Interventions addressing EF may improve dietary adherence in pediatric CD.