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Serotype 3 pneumococcal pleural empyema: a case report and review of the epidemiology
Maja Thoustrup Legardt Johansen1,2, Frederikke Kristensen Lomholt3, Jens-Ulrik Stæhr Jensen2,4
1Department of Respiratory Medicine and Infectious Diseases, Copenhagen University Hospital, North Zealand, Denmark.
Abstract:
Serotype 3 pneumococcal infection can cause severe invasive disease, even in immunocompetent adults, and is potentially preventable by vaccination. Invasive pneumococcal disease caused by serotype 3 is currently the most frequent serotype found in adults in Denmark. In this report, we present a 62-year-old immunocompetent man diagnosed with a severe pleural empyema caused by serotype 3, requiring a long course of antibiotics. The patient experienced clinical improvement, and follow-up imaging showed near-complete resolution of lung infiltrates. We also review the epidemiology of serotype 3 invasive pneumococcal disease in adults in Denmark and discuss the challenges related to serotype 3 and effective vaccines.
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