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Quantifying Intermembrane Distances with Serial Image Dilations
Published on: September 28, 2018
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1Departments of Computational Medicine, Human Genetics, and Statistics, University of California, Los Angeles, CA 90095, USA.
Summary
This study introduces Frank-Wolfe and projected gradient ascent algorithms to find the diameter and farthest point in convex sets. A homotopy method improves projected gradient ascent
Area of Science:
- Optimization Algorithms
- Computational Geometry
- Convex Analysis
Background:
- Determining the diameter and farthest point in compact convex sets are fundamental problems in optimization.
- Existing algorithms like Frank-Wolfe and projected gradient ascent can be trapped in local maxima for non-convex problems.
Purpose of the Study:
- To propose and test novel algorithms for computing the diameter and farthest point of compact convex sets.
- To investigate the efficacy of a homotopy method in overcoming local maxima limitations of gradient-based algorithms.
Main Methods:
- Construction and testing of Frank-Wolfe and projected gradient ascent algorithms.
- Development and application of a homotopy method to gradually deform a ball into the target set.
- Calculation of support functions for intersections of convex cones and balls, and for convex sublevel sets.
Main Results:
- Frank-Wolfe and projected gradient ascent algorithms demonstrate comparable performance on tested compact convex sets.
- The Frank-Wolfe algorithm shows greater reliability when the homotopy method is not employed.
- The homotopy method enhances the projected gradient ascent algorithm, enabling it to recover from failures.
Conclusions:
- Both Frank-Wolfe and projected gradient ascent are viable for diameter and farthest point computations.
- Homotopy methods offer a significant improvement for projected gradient ascent, increasing its robustness.
- The study contributes refined algorithmic approaches for geometric optimization problems.
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