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Rehabilitation applications and progress in managing pulmonary hypertension

Yuyan Liu^1,2, Xiao Guo^1,2, Panpan Liu³

¹Rehabilitation Medicine College, Shandong Second Medical University, Weifang, China.

Frontiers in Medicine

|September 2, 2025

Summary

Pulmonary hypertension rehabilitation therapy improves exercise capacity and quality of life. This non-pharmacological approach enhances physical and psychological well-being for patients with pulmonary hypertension (PH).

Area of Science:

Cardiology and Respiratory Medicine
Rehabilitation Science

Background:

Pulmonary hypertension (PH) significantly impairs exercise tolerance and quality of life.
Pharmacological treatments improve symptoms but do not fully address functional limitations.
Rehabilitation therapy emerges as a crucial non-pharmacological intervention for PH management.

Purpose of the Study:

To review the role and advancements of rehabilitation therapy in managing pulmonary hypertension.
To highlight the effectiveness of rehabilitation in improving patient outcomes and quality of life.
To explore future directions in PH rehabilitation.

Main Methods:

Comprehensive review of clinical features, prevalence, and treatment of PH.
Focus on diverse rehabilitation modalities: exercise training, inspiratory muscle training, neuromuscular electrical stimulation, and psychological support.
Analysis of emerging evidence on the safety and efficacy of rehabilitation interventions.

Main Results:

Rehabilitation therapy is safe and effective in enhancing cardiopulmonary function, muscle strength, and exercise capacity in PH patients.
Interventions alleviate key symptoms like dyspnea, anxiety, and depression.
Improved quality of life and reintegration into social roles are observed.

Conclusions:

Rehabilitation therapy offers significant benefits for individuals with pulmonary hypertension.
It complements pharmacological approaches by improving physical, psychological, and social functioning.
Further research and innovative approaches are needed to optimize PH management through rehabilitation.

Keywords:

exercise exercise limitation pulmonary hypertension quality of life rehabilitation

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