Related Experiment Video
Updated: Sep 9, 2025

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
Resource Allocation in the Pediatric Intensive Care Unit in Rwanda
Tracy Kelly1, Owen Selden1, Dazhanae Houston1
1University of Virginia, Charlottesville, Virginia, USA.
Insights
Critically ill children in Rwanda face high mortality rates, with sepsis and respiratory failure being common causes. Delays in treatment and surgery in newborns significantly increase the risk of death in pediatric intensive care units (PICUs).
Area of Science:
- Pediatric critical care
- Global child health
- Resource allocation in healthcare
Background:
- Children in low- and middle-income countries (LMICs) have a disproportionately higher mortality rate before age five compared to those in high-income countries.
- Pediatric Intensive Care Units (PICUs) improve outcomes, but resource limitations in LMICs hinder access to care for critically ill children.
- Understanding the specific challenges in LMIC PICUs is crucial for developing targeted interventions.
Purpose of the Study:
- To determine the disease burden of patients admitted to the Pediatric Intensive Care Unit (PICU) at Central Hospital in Kigali, Rwanda.
- To analyze the relationship between patient mortality and resource allocation within the PICU.
- To investigate the impact of factors such as health system entry point, admission delays, and surgical status on mortality rates.
Main Methods:
- A retrospective, cross-sectional review of 177 patient records from January 2016 to December 2022.
- Data extraction included demographic and clinical information.
- Descriptive and inferential statistics, including univariable and multivariable logistic regression, were used to identify mortality predictors.
Main Results:
- The overall mortality rate in the PICU was 55%.
- Sepsis, primary respiratory failure, and congenital defects were the most frequent causes of death.
- Delayed PICU admission was associated with increased odds of mortality. An interaction between age and surgery showed higher mortality in newborns compared to older infants when surgery was performed.
Conclusions:
- Adherence to pediatric sepsis guidelines, prompt recognition, and effective treatment are vital for reducing mortality.
- Policies aimed at minimizing delays in critical care access for children can significantly improve survival rates.
- Addressing specific risk factors like delayed admission and surgical timing in vulnerable populations (e.g., neonates) is essential.
Abstract:
Background: Children born in low‑ and middle‑income countries are 14 times more likely to die before reaching the age of five compared to children in high‑income countries. Pediatric Intensive Care Units (PICUs) with specialized equipment and advanced medications managed by trained clinicians have reduced mortality of children worldwide, yet countries with limited funds and scarce resources strain to meet needs of critically ill children. Objectives: The aim of the study was to identify the disease burden of patients entering the PICU at the Central Hospital in Kigali, Rwanda, and the relationship between patient mortality and allocation of resources. In addition, this study focused on several factors suspected to impact the mortality rate, including the entry point into the health system, delay in admittance, and whether surgery was performed. Method: A retrospective, cross‑sectional review of 30 medical records per year was conducted between January 2016 and December 2022, totaling 177 encounters. Demographic and clinical data were extracted and analyzed to perform descriptive and inferential statistics, including univariable and multivariable logistic regression analyses to identify factors affecting mortality. Findings: The study showed an overall mortality rate of 55% for patients admitted to the PICU. Among patients who died, the most common diagnoses were sepsis, primary respiratory failure, and congenital defects. When holding age and surgery constant, patients with a noted delay in admittance to the PICU had increased odds of mortality than those without a delay. Holding the delay in admittance constant, there was an interaction effect between age and surgery on mortality, with higher odds of mortality in newborns than in children over one month of age when surgery was performed. Conclusions: Careful adherence to emerging pediatric sepsis guidelines, immediate recognition, and appropriate treatment may reduce mortality. Prioritizing policies that reduce delays in treating critically ill children may improve outcomes.
Related Concept Videos
Acute Kidney Injury V: Interprofessional Care
Continuous Renal Replacement Therapy
Acute Kidney Injury VI: Nursing Management
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:

