[Aspergillosis with involvement of the central nervous system]

Clinical and pathological findings in a patient with central nervous system lesions due to a disseminated aspergillosis are reported. Symptoms and signs were suggestive of a meningoencephalitis with onset two years after nephrectomy for cancer and four months after a corticotherapy was started for post-radiation digestive disorders. A review of the literature shows that C.N.S. is rarely involved in this disease, that the diagnosis is difficult in immunodepressed patients and that the prognosis is poor in the absence of a specific treatment.