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Updated: Sep 9, 2025
Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
Refractory granulomatous lobular mastitis associated with subpectoral abscess and localized Salmonella infection: A
Keiko Kubota1, Takashi Kurabayashi1, Masanori Tasaki2
1Department of Plastic and Reconstructive Surgery, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321-0293, Japan.
Abstract:
We report a rare granulomatous lobular mastitis (GLM) associated with Salmonella spp. infection in a 41-year-old woman presenting as a subpectoral abscess. Diagnosis was delayed due to negative routine cultures and atypical presentation. Surgical excision combined with long-term levofloxacin therapy achieved full recovery. Effective treatment requires antimicrobial coverage and elimination of static secretions in the mammary gland to prevent recurrence. Our case presents a unique perspective by illustrating how Salmonella, a facultative intracellular pathogen that targets macrophages and other immune cells, may secondarily infect a GLM lesion, characterized by dense infiltration of immune cells.
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