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Long-term follow-up in chronic non-obstructive pyelonephritis. A retrospective radiological study
Scandinavian Journal of Urology and Nephrology
|January 1, 1985
Summary
Chronic non-obstructive pyelonephritis scarring primarily occurs in childhood and adolescence. Progression is rare without additional factors like kidney stones, with most cases stabilizing in adulthood.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Urology
Background:
- Chronic non-obstructive pyelonephritis is a significant renal condition.
- Long-term outcomes and progression factors require further elucidation.
Purpose of the Study:
- To investigate the long-term progression of chronic non-obstructive pyelonephritis.
- To identify factors influencing renal scarring in adult and pediatric patients.
Main Methods:
- Retrospective study of 15 adults and 8 children with chronic non-obstructive pyelonephritis.
- Follow-up periods ranged from 18 to 40 years (mean 25 years).
- Utilized serial urographies and clinical examinations for patient monitoring.
Main Results:
- In adults, progressive scarring was observed in 3 patients with renal calculi; others remained stable.
- In children, all affected kidneys showed progressive scarring during childhood and adolescence.
- Scarring stabilized in adulthood for pediatric patients, irrespective of initial severity.
Conclusions:
- Calyceal clubbing and parenchymal scarring develop during childhood.
- Progression of renal scarring is uncommon without superimposed factors, notably renal stone formation.
- The findings highlight the importance of early childhood factors in chronic pyelonephritis outcomes.