Hepatic Epithelioid Hemangioendothelioma: A Rare Vascular Neoplasm of the Liver

Epithelioid hemangioendothelioma (EHE) is a rare vascular neoplasm that can involve multiple organs. Most cases are asymptomatic and detected incidentally, but the clinical course can vary significantly. A 40-year-old man presented with abdominal and chest pain; imaging revealed large hepatic masses along with pulmonary nodules. Histopathological examination confirmed the diagnosis of EHE, with positivity for endothelial markers. Given the extent of the disease, systemic therapy was planned. This case highlights the challenges in diagnosing EHE and underscores the need for an individualized approach to managing this rare tumor.