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Related Concept Videos

Infertility in Males01:23

Infertility in Males

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Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
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Spermatogenesis01:41

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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A complete procedure of testing the hypothesis about a population mean is explained here.
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Updated: Sep 9, 2025

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
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Does abnormal weight affect sperm quality? A case-control study based on bioelectrical impedance analysis.

Huang Liu1, Xiaoxia Wang2, Li Li3

  • 1Department of Andrology, National Health Commission (NHC) Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute (Guangdong Provincial Fertility Hospital), Human Sperm Bank of Guangdong Province, Guangzhou, China.

Frontiers in Nutrition
|September 2, 2025
PubMed
Summary
This summary is machine-generated.

Abnormal body weight impacts male fertility, with body composition metrics like percent body fat and InBody score being more indicative than BMI. Bioelectrical impedance analysis can help predict sperm parameters.

Keywords:
BMIbioelectrical impedance analysisbody compositionsperm parametersspermatogenesis

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Area of Science:

  • Reproductive Medicine
  • Andrology
  • Body Composition Analysis

Background:

  • Obesity and abnormal weight are linked to metabolic, circulatory, and systemic changes.
  • The association between aberrant weight and male fertility is a growing area of research, though findings remain debated.
  • Understanding these correlations is crucial for male reproductive health assessments.

Purpose of the Study:

  • To evaluate the correlation between abnormal body weight and sperm quality using bioelectrical impedance analysis.
  • To determine the extent to which abnormal weight influences sperm quality.
  • To explore predictive markers for sperm quality beyond traditional metrics.

Main Methods:

  • A retrospective case-control study of 137 men undergoing fertility assessment.
  • Analysis of sperm parameters and detailed body composition metrics via bioelectrical impedance analysis.
  • Statistical analysis including Pearson correlation and factor analysis to identify key influencing factors.

Main Results:

  • Body composition parameters did not differ significantly between groups with varying sperm counts (A, B, C).
  • Significant differences in age, weight, and various body composition metrics were observed between groups with and without sperm (AA vs. BB).
  • Factor analysis identified age, InBody score (IBS), percent body fat (PBF), weight, and height as key factors, with age, IBS, and PBF being more sensitive than BMI.

Conclusions:

  • Body composition significantly impacts sperm quality, with age, IBS, and PBF showing higher predictive accuracy than BMI.
  • Bioelectrical impedance analysis offers a valuable tool for assessing and potentially predicting male sperm parameters.
  • These findings suggest a refined approach to evaluating male fertility in relation to body composition.