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Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement

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Minimally Invasive Techniques for Nasal Valve Dysfunction: A Systematic Review and Meta-Analysis.

Guled M Jama¹, Filippo Cainelli², Luiza Farache Trajano³

¹Department of Rhinology and Facial Plastic Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

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|September 2, 2025

Summary

This summary is machine-generated.

Minimally invasive treatments for nasal valve dysfunction (NVD) offer significant symptom relief and are well-tolerated. These office-based options provide durable improvements, presenting viable alternatives to traditional surgery for nasal obstruction.

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Area of Science:

Otolaryngology
Minimally Invasive Surgery
Rhinology

Background:

Nasal valve dysfunction (NVD) is a common cause of nasal obstruction, impacting patient quality of life.
Office-based interventions are emerging as alternatives to traditional surgery for NVD.
Comparative safety and efficacy of these new treatments require further evaluation.

Purpose of the Study:

To systematically review and meta-analyze the safety and efficacy of minimally invasive office-based interventions for NVD.
To assess patient-reported outcomes, including Nasal Obstruction Symptom Evaluation (NOSE) and Visual Analog Scale (VAS) scores.
To compare different minimally invasive techniques for NVD treatment.

Main Methods:

Systematic review and meta-analysis following PRISMA guidelines.
Searched four databases (PubMed, Scopus, Cochrane Library, Ovid) for studies from 2005-2025.
Included 15 studies (546 patients) evaluating temperature-controlled radiofrequency (TCRF), bioabsorbable implants, suturing, and stenting.

Main Results:

All evaluated interventions (TCRF, implants, suturing) showed statistically significant improvements in NOSE and VAS scores.
Temperature-controlled radiofrequency (TCRF) demonstrated a weighted mean difference (WMD) of -44.68 in NOSE scores (p < 0.001).
Improvements were sustained for 3-48 months, with mild and transient adverse events.

Conclusions:

Minimally invasive techniques for NVD provide significant, clinically important, and durable symptom relief.
These interventions have favorable safety profiles and may be suitable alternatives to traditional surgery.
Future research should focus on randomized controlled trials and standardized outcome measures.