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Updated: Sep 9, 2025

Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome ARDS
Published on: April 7, 2021
Acute respiratory distress syndrome: Why a definition matters
Christine Girard1, Divyajot Sadana2, Shewit Giovanni3
1Department of Pulmonary and Critical Care Medicine, Cleveland Clinic, Cleveland, OH.
None:
The definition of acute respiratory distress syndrome (ARDS) has been updated several times since the syndrome was first described in 1967. The aim of the initial definition was to better study this disease and standardize its care. Each iteration has brought its own set of nuances and challenges. In 2024, a new global definition of ARDS was proposed. This review highlights the evolution of ARDS definitions over the years and discusses the key components of the new proposed global definition.
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