Related Experiment Video
Updated: May 6, 2026

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues
Published on: May 1, 2019
Analysis of system and scanner downtime in a digital pathology-predominant institution: A 6-year experience
Ryan Reagans1, Lokman Cevik1, Himani Kumar1
1Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, United States.
Objective:
To determine trends in system and scanner downtime in our institution's digital pathology pipeline since its implementation.
Methods:
Scanner and system downtime data were tabulated from a period beginning in 2017 and ending in 2022. Downtime events were categorized based on their etiology, such as image management system related for the overall system or hardware vs software related for the scanner.
Results:
The maximum scanner downtime consisted of 36 events and occurred in the first quarter of 2019; most of this downtime was attributed to hardware issues. The average scanner downtime per quarter was 350.7 hours. Multifactorial events tended to last longer than single events. System downtime was mostly due to the image management system. Full-system downtime occurred from 2017 through 2019; since then, full-system downtime has essentially been replaced with partial downtime.
Conclusions:
Scanner downtime was mostly due to hardware, while system downtime was mostly caused by issues with the image management system. With experience, our institution mitigated the impact of technological difficulties, significantly reducing the number of downtime events since the implementation of digital pathology in 2017.
Related Concept Videos
Effects of EDTA on End-Point Detection Methods
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
Automated Microbial Diagnostics

