Development and validation of a comprehensive risk warning indicator system for depression in Chinese children and

Yan Han1, Jingrong Xi, Huizhu Jiang

  • 1Huai'an No. 3 People's Hospital, Huai'an City, Jiangsu, China.

Medicine
|September 3, 2025
PubMed

Insights

This study developed a culturally appropriate system to detect depression in Chinese youth. The validated indicator system shows high reliability and content validity for early identification and intervention.

Area of Science:

  • Child and Adolescent Psychiatry
  • Mental Health Screening
  • Psychometric Validation

Background:

  • Childhood depression is a global epidemic requiring effective early detection.
  • Existing screening tools lack cultural appropriateness and comprehensive frameworks for Chinese pediatric populations.

Purpose of the Study:

  • To develop and validate a comprehensive, culturally appropriate risk warning indicator system for depression detection in Chinese children and adolescents.

Main Methods:

  • Mixed-methods approach: systematic literature review, expert Delphi consultations (2 rounds), and empirical validation.
  • Analytic hierarchy process for indicator weighting; psychometric validation with 386 depressed youth (ages 11-18).

Main Results:

  • A 5-domain, 38-indicator system developed with expert consensus (authority coefficients 0.808-0.868, consensus P < .001).
  • Key domains: language (0.347), emotion (0.251), behavior (0.190), stress events (0.144), history (0.068).
  • System demonstrated robust reliability (KR-20=0.811, ICC=0.832) and high content validity (S-CVI/Ave=0.995).

Conclusions:

  • The developed indicator system is scientifically rigorous, culturally sensitive, and psychometrically sound.
  • It offers practical applicability for early depression detection in clinical, educational, and community settings.
  • Potential to improve prevention and intervention outcomes for vulnerable youth.