A strategy for constructing chiral covalent organic frameworks from achiral crystalline precursors
Hui-Chao Ma1, Jing-Ru Li1, Xue-Tian Li1
1College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China. huichaoma@sdnu.edu.cn.
None:
A rational chiral covalent organic framework (CCOF) synthesis strategy is essential to unlock their potential applications. In this work, a new method was developed for the synthesis of crystalline CCOFs, R/S-PPI-2-COF (P6 space group), which were transformed from the achiral PI-2-COF. To demonstrate the generality of the synthetic strategy, two additional reported achiral COFs (PI-3-COF and COFTFPY-PPDA) were also converted into CCOFs. Notably, R-PPI-2-COF with its nitrogen- and oxygen-rich framework exhibits high porosity and enables enantioselective separation of racemic methyl mandelate.
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