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Area of Science:

  • Gerontology
  • Pharmacology
  • Public Health

Background:

  • Home medical care is essential for aging populations.
  • Potentially inappropriate medications (PIMs) pose risks to older adults.
  • Understanding PIM prevalence in homebound elderly is critical for patient safety.

Purpose of the Study:

  • To determine demographic characteristics of care-dependent older adults receiving home medical care.
  • To assess the association between PIM prescriptions and hospitalization or death in this population.

Main Methods:

  • Retrospective analysis of health insurance claims data from older adults (≥65 years) in Kure City, Japan.
  • Inclusion of demographic data, diagnoses, long-term care (LTC) needs, and medication profiles.
  • Statistical analysis using logistic regression to identify factors associated with hospitalization and death, with PIMs defined by STOPP-J criteria.

Main Results:

  • 2052 participants (mean age 86.5 years, 71.7% female) were included.
  • PIM prevalence increased with higher LTC needs (up to 26.0%).
  • Number of medications, PIMs, and moderate care levels were linked to increased hospital admission risk.

Conclusions:

  • Potentially inappropriate medications are prevalent in homebound older adults.
  • Disability level and polypharmacy are associated with higher hospitalization rates.
  • Regular medication reviews are recommended for this vulnerable population.