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CroPCS: Crop Plants Combined Stress Knowledgebase.

Akash DAS1, Drishtee Barua1,2, Souvik Pal3

  • 1Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, India.

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|September 3, 2025
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Summary
This summary is machine-generated.

This study introduces the Crop Plants Combined Stress Knowledgebase (CroPCS), a vital resource for plant stress research. It consolidates OMICS data on crop responses to combined stresses, aiding climate change adaptation strategies.

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Area of Science:

  • Plant Science
  • Bioinformatics
  • Genomics

Background:

  • Plants face combined biotic and abiotic stresses, exacerbated by climate change.
  • Existing OMICS data on plant stress responses is fragmented and inaccessible.
  • There is a critical need for integrated, publicly available data repositories.

Purpose of the Study:

  • To develop a manually curated knowledgebase (CroPCS) for crop plant responses to combined stresses.
  • To provide a user-friendly platform for accessing and querying molecular data.
  • To facilitate research on plant adaptation to environmental challenges.

Main Methods:

  • Manual biocuration of OMICS literature.
  • Integration of data on genes, proteins, metabolites, and non-coding RNAs.
  • Development of a searchable online repository with a user-friendly interface.

Main Results:

  • CroPCS version 1 includes 13 crop plants and 16 stress combinations.
  • The database contains 266,417 molecules: 262,220 genes, 1709 proteins, 274 metabolites, and 2214 ncRNAs.
  • The resource supports community curation, allowing user data submissions.

Conclusions:

  • CroPCS is a unique, comprehensive online resource for plant stress research.
  • It enhances accessibility of critical molecular data for crop improvement.
  • The knowledgebase supports research into plant resilience under combined environmental stresses.