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Updated: May 2, 2026

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Published on: May 23, 2011
Noninvasive Brain Stimulation and Pain Neuroscience Education for Fibromyalgia and Trigeminal Neuralgia: A Case
1High Point University, High Point, NC.
Background:
Fibromyalgia (FM) and trigeminal neuralgia (TN) are commonly mistreated pain diagnoses that often present significant cognitive-affective impairments. .
Case Report:
A 22-year-old woman with diagnoses of FM and TN underwent 5 sessions of 2 mA transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex for 20 minutes followed by ~20 minutes of pain neuroscience education (PNE). Following 5 sessions, the patient reported resolution of TN-related symptoms and improvement of generalized pain, fatigue, and sensitivity. The patient demonstrated a 60% reduction in self-reported pain, 65% in pain catastrophizing, 24% in kinesiophobia, 28% in central sensitization, and 33% improvement in attentional interference.
Conclusion:
The case study demonstrates positive effect of tDCS and PNE in the management of FM and TN. Interventions primarily targeted the cognitive-affective domains of pain, improving both cognitive-affective and sensory outcomes. tDCS + PNE may provide a novel combination of intervention for 2 historically ill-treated conditions.
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