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Updated: Sep 8, 2025

Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
Innovative utilization of argon plasma coagulation combined with endoclips for managing gastrointestinal bleeding
Zihan Huang1, Xiaomeng Feng1, Xin Yin1
1Department of Gastroenterology, Air Force Medical Center, Air Force Medical University, Beijing, China.
Background:
Colonic diverticular bleeding is one of the primary causes of lower gastrointestinal bleeding, with endoscopic hemostasis as the first-line treatment. However, the outcomes of endoscopic treatments remain suboptimal. This study utilized an innovative therapeutic method to manage colonic diverticular bleeding and evaluated its feasibility and safety in clinical settings.
Methods:
Between July 2018 and July 2023, 35 patients with colonic divercular bleeding were treated through argon plasma coagulation combined with endoclips (APC-EC) at the Air Force Medical Center. The technical success rate, rebleeding rate, and complications associated with the therapeutic method over a 5-year period were retrospectively analyzed.
Results:
The technical success rate of the method was 100%, the early rebleeding rate of APC-EC was 8.57%. The incidence of late rebleeding at 1-year follow-up was 5.71%, it was 0% at the 2- and 3-year follow-up periods. Intraoperative perforation was observed only in two patients treated with APC-EC; however, delayed perforation was not observed in any patient, and none of them required surgical treatment.
Conclusions:
APC-EC might be a viable, safe, and effective method for treating colonic divercular bleeding.
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