Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chirality at Nitrogen, Phosphorus, and Sulfur02:30

Chirality at Nitrogen, Phosphorus, and Sulfur

5.9K
Chirality is most prevalent in carbon-based tetrahedral compounds, but this important facet of molecular symmetry extends to sp3-hybridized nitrogen, phosphorus and sulfur centers, including trivalent molecules with lone pairs. Here, the lone pair behaves as a functional group in addition to the other three substituents to form an analogous tetrahedral center that can be chiral.
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
5.9K
Prochirality02:05

Prochirality

3.9K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
3.9K
Chirality02:25

Chirality

25.2K
Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
25.2K
Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

12.1K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
12.1K
¹H NMR Chemical Shift Equivalence: Enantiotopic and Diastereotopic Protons00:58

¹H NMR Chemical Shift Equivalence: Enantiotopic and Diastereotopic Protons

1.9K
Replacing each alpha-hydrogen in chloroethane by bromine (or a different functional group) yields a pair of enantiomers. Such protons are called prochiral or enantiotopic and are related by a mirror plane. Enantiotopic protons are chemically equivalent in an achiral environment. Because most proton NMR spectra are recorded using achiral solvents, enantiotopic hydrogens yield a single signal.
In chiral compounds such as 2-butanol, replacing the methylene hydrogens at C3 produces a pair of...
1.9K
Chirality in Nature02:30

Chirality in Nature

13.8K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
13.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Binding Affinity Determines the Success of Endogenous Cu<sup>II</sup>-NTA Spin Labeling for In-Cell Electron Paramagnetic Resonance Distance Measurements.

The journal of physical chemistry letters·2026
Same author

Implementing the Quantum Fourier Transform on a molecular qudit with full refocusing and state tomography.

Nature communications·2026
Same author

Persistent compensated ferrimagnetism in the molecular framework Cr(pyrazine)<sub>3</sub>.

Nature chemistry·2026
Same authorSame journal

Crystallographic and EPR-based characterisation of Cu<sup>2+</sup>-binding to serum albumin: ATCUN coordination and additional sites.

Inorganic chemistry frontiers·2026
Same author

Swapped and non-swapped TRAAK states co-exist in membranes at a ratio influenced by temperature.

Nature communications·2026
Same author

Effect of Chemical Modification in Trigonal Gd(III) Molecular Qubits.

Inorganic chemistry·2025
Same journal

Picolinamide-functionalized macrocyclic chelators for <sup>203/212</sup>Pb theranostic radiotracers.

Inorganic chemistry frontiers·2026
Same journal

Cytotoxicity and immunogenic cell death studies of water-soluble tetrahedral Ga(iii) or Fe(iii) coordination cages containing a Au(i) anticancer drug as guest.

Inorganic chemistry frontiers·2026
Same journal

Structural insights into <i>ortho</i>-aminophenol oxidases: kinetic and crystallographic characterization of <i>Sm</i>NspF and <i>Sg</i>GriF.

Inorganic chemistry frontiers·2026
Same journal

Competitive LC-MS/MS assay to investigate protein metalation dynamics.

Inorganic chemistry frontiers·2026
Same journal

Lewis superacids for catalytic reductions of stronger element-oxygen double bonds with hydrosilanes.

Inorganic chemistry frontiers·2026
See all related articles
  1. Home
  3. Chiral Molecular 4f Qubits By Post Functionalization.
  1. Home
  3. Chiral Molecular 4f Qubits By Post Functionalization.

Related Experiment Video

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
07:50

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

9.4K

Chiral molecular 4f qubits by post functionalization.

Steen H Hansen1, Christian D Buch1, Bela E Bode2

  • 1Department of Chemistry, University of Copenhagen Universitetsparken 5 2100 Denmark piligkos@chem.ku.dk.

Inorganic Chemistry Frontiers
|September 3, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Researchers synthesized enantiomerically pure ytterbium(III) complexes using chiral amines. These chiral ytterbium(III) complexes exhibit distinct spectroscopic properties and long electronic spin coherence times, crucial for quantum applications.

More Related Videos

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K
Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.1K

Related Experiment Videos

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
07:50

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Published on: May 26, 2019

9.4K
Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K
Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.1K

Area of Science:

  • Coordination Chemistry
  • Materials Science
  • Quantum Information Science

Background:

  • Chiral lanthanide complexes are of interest for optical and magnetic applications.
  • Controlling the chirality and electronic properties of lanthanide complexes is essential for developing advanced materials.

Purpose of the Study:

  • To synthesize and characterize enantiomerically pure ytterbium(III) complexes.
  • To investigate the spectroscopic and spin properties of these chiral ytterbium(III) complexes.

Main Methods:

  • Post-functionalization of a parent Yb(III) complex via condensation with a chiral amine.
  • Single crystal and powder X-ray diffraction for structural characterization.
  • Near-infrared (NIR) Circular Dichroism (CD) and absorption spectroscopy.
  • X-band pulse Electron Paramagnetic Resonance (EPR) spectroscopy on magnetically dilute single crystals.

    • Main Results:

    • Successful synthesis of an enantiomeric pair of Yb(III) complexes, confirmed by X-ray diffraction in the P212121 space group with Flack parameters near zero.
    • Observation of sharp f-f transitions in NIR CD and absorption spectra, indicating a chiral ytterbium environment with g_abs values up to 0.07.
    • EPR spectroscopy revealed a phase memory time (T_m) of 600 ns for the electronic spin and demonstrated coherent manipulation via microwave pulses (Rabi nutations).

    Conclusions:

    • Enantiomerically pure Yb(III) complexes can be synthesized through post-functionalization.
    • These chiral complexes possess unique optical properties and exhibit long spin coherence, making them promising for quantum technologies.
    • The study highlights the potential of chiral lanthanide complexes in areas like quantum computing and sensing.