Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ankle Joint

Ankle Joint

The ankle is formed by the talocrural joint (crural = leg). It consists of the articulations between the talus bone of the foot and the distal ends of the tibia and fibula of the leg. The superior aspect of the talus bone is square-shaped and has three areas of articulation. The top of the talus articulates with the inferior tibia. This is the portion of the ankle joint that carries the body weight between the leg and foot. The sides of the talus are firmly held in position by the articulations...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Fracture table vs. lateral positioning for intramedullary fixation of femur fractures (The FLiP Trial): the feasibility of a cluster randomized crossover trial.

Pilot and feasibility studies·2026

Same author

Exploratory Assessment of Muscle Thickness and Stiffness Around Arteriovenous Fistulas Using Shear Wave Elastography.

Journal of clinical medicine·2025

Same author

Scoping review for treatment of osteolysis in total ankle arthroplasty.

BMC musculoskeletal disorders·2025

Same author

Correction: Patient and surgical factors affecting recovery after femur fracture fixation: a secondary analysis of the FLiP trial.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2025

Same author

Patient and surgical factors affecting recovery after femur fracture fixation: a secondary analysis of the FLiP trial.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2025

Same author

Fracture Table vs. Lateral Positioning for Antegrade Intramedullary Fixation of Femur Fractures (The FLiP Study): The Clinical Outcomes of a Multi-Centre Cluster Randomized Crossover Pilot Study.

Journal of orthopaedic trauma·2025

Same journal

Impact of Diagnosed Mental Health Disorders on Postoperative Outcomes After Achilles Tendon Repair.

Foot & ankle orthopaedics·2026

Same journal

Metatarsus Adductus Association With Fifth Metatarsal Fractures: Radiographic Analysis.

Foot & ankle orthopaedics·2026

Same journal

Percutaneous Debridement and Double-Row Repair for Insertional Achilles Tendinopathy With Immediate Postoperative Weightbearing: A Consecutive Case Series.

Foot & ankle orthopaedics·2026

Same journal

PROMIS Computerized Adaptive Testing Demonstrates Strong Convergent Validity and Lower Patient Burden Compared With Legacy Instruments in Foot and Ankle Fracture Care.

Foot & ankle orthopaedics·2026

Same journal

Depth of the Dorsalis Pedis Artery Distal to the First and Second Tarsometatarsal Joints: A Cadaveric Anatomical Study.

Foot & ankle orthopaedics·2026

Same journal

Implications of Size and Gender for Implant Fit and Coverage in Total Ankle Replacement.

Foot & ankle orthopaedics·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Sep 9, 2025

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Osteolysis After HINTEGRA Total Ankle Replacement: Radiographic Patterns, Alignment Associations, and Long-Term

Eric Locke¹, Roxane Heroux-Legault¹, Maram Alothman^2,3

¹Division of Orthopaedic Surgery, University of Ottawa, Ottawa, ON, Canada.

Foot & Ankle Orthopaedics

|September 3, 2025

Summary

This summary is machine-generated.

Osteolysis is common after total ankle replacement (TAR) with the HINTEGRA prosthesis, often appearing years after surgery. Progressive cysts and malalignment may increase revision risk, but most cases do not lead to failure.

Keywords:

HINTEGRA osteolysis total ankle replacement

More Related Videos

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Published on: February 27, 2018

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

Related Experiment Videos

Last Updated: Sep 9, 2025

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach

Published on: January 24, 2018

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Individualized Stem-positioning in Calcar-guided Short-stem Total Hip Arthroplasty

Published on: February 27, 2018

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

Area of Science:

Orthopedic surgery
Biomaterials science
Radiology

Background:

Total ankle replacement (TAR) is a surgical option for end-stage ankle arthritis.
Osteolysis leading to aseptic loosening remains a significant cause of TAR failure.
The HINTEGRA prosthesis is a commonly used implant for TAR.

Purpose of the Study:

To evaluate the incidence and outcomes of osteolysis after HINTEGRA total ankle replacement.
To identify risk factors associated with osteolysis and its clinical sequelae.

Main Methods:

Retrospective review of 51 HINTEGRA TARs performed between 2006 and 2014.
Radiographic assessment for implant positioning, osteolytic cyst presence, location, and progression.
Correlation of osteolysis with reoperation and revision rates.

Main Results:

Eighty-four osteolytic cysts were identified in 37 patients over an average follow-up of 5.8 years.
Cyst number and size increased with time post-surgery, most commonly in the posterior tibia.
Progressive cysts and coronal malalignment were associated with reoperation, though most cysts did not cause clinical failure.

Conclusions:

Osteolysis is a frequent radiographic finding in HINTEGRA TARs, particularly with long-term follow-up.
Progressive osteolysis and prosthesis malalignment are potential risk factors for implant loosening and reoperation.
While most osteolytic lesions are asymptomatic, significant progression warrants close monitoring.