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Use of Infrared Thermography in Visualizing Erythema Migrans.
Natalia I Brothers1, Alison Rebman1, Jonathan M Zenilman1
1Lyme Disease Research Center, Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, USA.
Cureus
|September 3, 2025
Summary
Infrared thermography (IRT) can detect erythema migrans (EM) in Lyme disease patients. This novel approach visualizes heat patterns, aiding in the identification of EM lesions.
Area of Science:
- Medical Imaging
- Dermatology
- Infectious Diseases
Background:
- Infrared thermography (IRT) is a non-invasive imaging technique that visualizes surface body heat patterns.
- IRT detects temperature deviations linked to increased peripheral perfusion.
- The application of IRT in diagnosing Lyme disease is a novel area of research.
Observation:
- This study examined three case examples of Lyme disease patients.
- Erythema migrans (EM) lesions were observed as areas of increased heat and prominent venous drainage.
- IRT imaging successfully identified both single and disseminated EM lesions.
Findings:
- IRT effectively visualizes the characteristic heat signatures of erythema migrans (EM) lesions.
- The technology can differentiate between normal skin temperature and the localized heat associated with EM.
- Prominent venous drainage patterns around EM lesions were discernible via IRT.
Implications:
- Infrared thermography shows potential as a valuable tool for improving the detection and understanding of Lyme disease's erythema migrans.
- This non-invasive method could aid clinicians in earlier and more accurate Lyme disease diagnosis.
- Further research into IRT applications may enhance diagnostic capabilities for various dermatological conditions.

