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Development of a biological at-risk volume using apparent diffusion coefficient for parotid-sparing radiation therapy

Katelyn Cahill1,2, Catriona Hargrave3,4, Patrick O'Connor1,5

  • 1Adem Crosby Centre-Radiation Oncology, Sunshine Coast University Hospital, Birtinya, QLD 4575, Australia.

BJR Open
|September 3, 2025
PubMed
Summary

This study shows that apparent diffusion coefficient (ADC) thresholds can identify radiosensitive areas in the parotid gland (PG) for head and neck cancer patients, potentially reducing xerostomia toxicity.

Keywords:
apparent diffusion coefficientbiological at-risk volumediffusion-weighted MRIhead and neck cancerparotid glandradiotherapy

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