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Effects of Daikin air purifiers on asthma control and pulmonary function: A multicenter, single-arm, observational
Satoshi Hamada1, Susumu Sato2, Shota Hori3
1Department of Advanced Medicine for Respiratory Failure, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan; Departement of Respiratory Medicine, Ayabe City Hospital, 20-1 Otsuka, Aono-cho, Ayabe, 623-0011, Japan.
Background:
While numerous studies, including systematic reviews, have investigated the effects of air purifiers on asthma control in Western countries, there is a paucity of research conducted in Japan. This multicenter, single-arm, observational pilot study examined the effect of air purifiers on asthma control in Japanese patients.
Methods:
This study was conducted at the Kyoto University Hospital and the Ayabe City Hospital. The air purifiers (MCK704ABK: Daikin Industries, Ltd., Osaka, Japan) were equipped with electrostatic high-efficiency particulate air filters, capable of capturing 99.97 % of particles ≥0.3 μm. We examined changes in particulate matter (PM) 2.5 levels and forced expiratory volume in 1 s (FEV1) before and after one month of air purifier use.
Results:
Eighteen patients (median age: 64 [58, 70] years, 66.7 % female) participated in the study. The median PM2.5 concentration significantly decreased from 4.6 (3.4, 6.9) μg/m3 to 1.4 (0.7, 2.7) μg/m3 after using the air purifiers (p = 0.00042). FEV1 significantly increased from 2.0 (1.7, 2.6) L to 2.1 (1.7, 2.6) L (p = 0.041). The median change in FEV1 after air purifier use was 40 (-22.5, 112.5) mL. Patients with improved FEV1 (ΔFEV1 >0 mL) had a significantly higher frequency of allergen sensitization compared to those without improvement (75.0 % vs. 16.7 %, p = 0.019).
Conclusion:
The Daikin air purifiers demonstrated the potential to reduce PM levels and improve pulmonary function and asthma symptoms.
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