Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

210
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
210
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

216
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
216
Management of Insomnia01:19

Management of Insomnia

320
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
320
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

289
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
289
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

238
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
238
Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurometabolic Stability and Heritability in the Adolescent Brain: A Preliminary Longitudinal Twin MRS Study.

NMR in biomedicine·2026
Same author

Sleep as a moderator of adolescent brain development-evidence from a longitudinal MRI study.

Sleep·2026
Same author

The infraslow fluctuation of sigma power during sleep in young individuals with schizophrenia.

Schizophrenia research·2025
Same author

The Infraslow Fluctuation of Sigma Power During Sleep in Young Individuals with Schizophrenia.

bioRxiv : the preprint server for biology·2025
Same author

The value of mental science: we publish what matters.

The British journal of psychiatry : the journal of mental science·2025
Same author

Joint Heritability of Sleep EEG Spindle Activity and Thalamic Volume in Early Adolescence.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2025

Related Experiment Video

Updated: Sep 9, 2025

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
03:46

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Published on: October 11, 2018

10.3K

Adolescent Sleep Disruption: Implications for Psychiatric Morbidity.

Leila Tarokh1, Carolina Guiterrez-Herrera2

  • 1Translational Research Center, University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland; University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Biological Psychiatry
|September 3, 2025
PubMed
Summary

Adolescent sleep problems are strongly linked to mental health issues due to brain development. Addressing sleep disturbances can improve psychiatric conditions and overall adolescent well-being.

Keywords:
AdolescenceBiomarkerDevelopmentElectroencephalogram (EEG)PsychiatrySleep

More Related Videos

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

791
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.5K

Related Experiment Videos

Last Updated: Sep 9, 2025

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling
03:46

Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

Published on: October 11, 2018

10.3K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

791
A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

5.5K

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Psychiatry

Background:

  • Adolescence is a critical period of brain development and increased risk for psychiatric disorders.
  • Sleep plays a crucial role in adolescent development and mental health.
  • Sleep disturbances are increasingly recognized as a potential factor in psychiatric vulnerability.

Purpose of the Study:

  • To review the pivotal role of sleep in adolescent development and its bidirectional relationship with mental health.
  • To explore how genetic and environmental factors link sleep disturbance to psychiatric vulnerability.
  • To advocate for integrated, developmentally informed approaches to treating psychiatric disorders, considering sleep as a diagnostic marker and therapeutic target.

Main Methods:

  • Literature review synthesizing current research on sleep, adolescent development, and psychiatric disorders.
  • Analysis of genetic and environmental factors influencing the sleep-mental health relationship.
  • Examination of transdiagnostic frameworks and intervention strategies.

Main Results:

  • Sleep disturbance is a significant factor linking genetic and environmental influences to psychiatric vulnerability in adolescents.
  • Sleep abnormalities are potential core features across various psychiatric conditions, supporting transdiagnostic approaches.
  • Behavioral and pharmacological interventions targeting sleep show promise for improving mental health outcomes.

Conclusions:

  • Sleep is a critical, yet often overlooked, factor in adolescent mental health and psychiatric disorders.
  • Integrated, developmentally informed interventions that target sleep are crucial for promoting adolescent resilience.
  • Multidisciplinary research is needed to fully understand causal pathways and optimize sleep-focused interventions.