Related Experiment Video
Updated: Sep 9, 2025

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
A pediatric health problem increasing with migration: pertussis reloading.
Sefika Aldas1, Murat Ersoy1, Berfin Ozgokce Ozmen1
1Department of Pediatrics, University of Health Sciences, Mersin City Education and Research Hospital Mersin, Mersin, Turkey.
Whooping cough (pertussis) poses a severe risk to infants, particularly unvaccinated and displaced populations. This study highlights the critical need for robust immunization programs and prompt medical intervention to combat this contagious respiratory illness.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Bordetella pertussis causes highly contagious respiratory infections, posing significant risks to infants.
- Vulnerable infant populations, including those displaced by events like refugee influxes or natural disasters, are particularly susceptible.
Purpose of the Study:
- To investigate the incidence and characteristics of pertussis (whooping cough) cases in infants following a refugee influx.
- To analyze the clinical presentation, treatment, and outcomes of hospitalized infants with pertussis.
Main Methods:
- Retrospective analysis of 28 infants hospitalized with pertussis between December 2023 and April 2024.
- Review of patient demographics, vaccination status, clinical symptoms, diagnostic findings (PCR, chest X-ray, blood work), treatments, and outcomes.
Main Results:
- 60.7% of infants were male, 39.3% of Syrian origin; 42.9% were unvaccinated.
- Common symptoms included respiratory distress, paroxysmal cough (96.4%), feeding difficulty (53.6%), and fever (32.1%).
- Severe complications like convulsions (10.7%), apnea (3.6%), pneumonic infiltrates (85.7%), and need for respiratory support (78.6%) were frequent; two infants died.
Conclusions:
- Pertussis remains a critical health concern for unvaccinated and displaced infants.
- Strengthening immunization coverage and ensuring timely diagnosis and treatment are vital for mitigating pertussis's impact.
- Public health strategies must address the needs of vulnerable populations during health crises.
More Related Videos
11:32Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
09:03Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
Related Concept Videos
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Vaccinations
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pulmonary Cycle: Exhalation