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Updated: Sep 9, 2025

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Published on: June 10, 2025
Racial and Ethnic Differences in Patient Age at First Hospitalization for Heart Failure
Xiaoning Huang1, Zachary Hughes1, Gregg C Fonarow2
1Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Racial and ethnic disparities exist in heart failure (HF) hospitalization age. Social and clinical factors significantly contribute to younger HF hospitalization ages in non-Hispanic Asian, non-Hispanic Black, and Hispanic patients compared to non-Hispanic White patients.
Area of Science:
- Cardiology
- Public Health
- Health Disparities
Background:
- Heart failure (HF) burden disproportionately affects various racial and ethnic groups.
- Understanding age-related disparities in HF is crucial for targeted interventions.
- Existing research highlights variations in HF prevalence and outcomes across diverse populations.
Purpose of the Study:
- To analyze the age of first heart failure (HF) hospitalization across different racial and ethnic groups.
- To quantify the impact of social risk factors on observed racial and ethnic differences in HF hospitalization age.
- To identify specific factors contributing to disparities in early HF onset.
Main Methods:
- Utilized data from the Get With The Guidelines-Heart Failure (GWTG-HF) registry (2016-2019).
- Included patients hospitalized for HF with no prior diagnosis.
- Employed Oaxaca-Blinder decomposition to assess contributions of clinical and social factors to age differences.
Main Results:
- Non-Hispanic (NH) Asian, NH Black, and Hispanic patients were significantly younger at first HF hospitalization than NH White patients.
- Average ages at first HF hospitalization: NH Asian (70.6), NH Black (60.1), Hispanic (65.4), NH White (73.6 years).
- Social and clinical factors accounted for substantial age differences: 1.2 years (NH Asian), 12.5 years (NH Black), and 7.4 years (Hispanic).
Conclusions:
- Non-Hispanic Asian, non-Hispanic Black, and Hispanic individuals experience first HF hospitalization at younger ages than NH White individuals.
- A significant portion of these age disparities is attributable to differences in social and clinical risk factors.
- Addressing social determinants of health is critical to mitigating HF disparities.
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