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Exploring the Nexus Between Ankle-Brachial Index and Atherosclerosis: A Bibliometric Analysis From 1989 to 2024

Jun Wang1, Yanfei Tao2, Yongjun Tao1

  • 1Department of Neurology, Municipal Hospital Affiliated to Taizhou University, Taizhou, 318000, People's Republic of China.

Journal of Multidisciplinary Healthcare
|September 4, 2025
PubMed

Insights

This bibliometric analysis reveals a growing research focus on the Ankle-Brachial Index (ABI) and atherosclerosis. Key trends highlight cardiovascular disease, mortality, and risk factors, guiding future atherosclerosis research.

Area of Science:

  • Cardiovascular Research
  • Bibliometrics
  • Epidemiology

Background:

  • Atherosclerosis-related cardiovascular and cerebrovascular diseases are a major global health concern.
  • The Ankle-Brachial Index (ABI) is a key non-invasive tool for diagnosing peripheral artery disease and assessing systemic atherosclerosis.
  • Understanding research trends in ABI and atherosclerosis is crucial for advancing cardiovascular health.

Purpose of the Study:

  • To conduct a bibliometric analysis of research on the Ankle-Brachial Index (ABI) and atherosclerosis.
  • To identify key contributors, influential publications, and evolving research trends.
  • To provide insights for future research directions in atherosclerosis and cardiovascular disease.

Main Methods:

  • Bibliometric analysis of publications from 1989 to 2024 using Web of Science Core Collection.
  • Data analysis employing R package "bibliometrix", CiteSpace, and VOSviewer.
  • Identification of research output, institutions, journals, authors, and keywords, including burst analysis.

Main Results:

  • A total of 1896 publications were analyzed, with a notable increase in research output peaking in 2021.
  • The United States led in publications and citations, with the University of California System as a leading institution.
  • Prominent journals included *Circulation* and *Atherosclerosis*, and Criqui Michael H. was the most cited author. Keywords like "cardiovascular disease", "mortality", and "risk factors" showed high co-occurrence.

Conclusions:

  • This bibliometric analysis provides a comprehensive overview of ABI research in atherosclerosis.
  • It highlights the growing importance of ABI in understanding cardiovascular disease burden and risk factors.
  • The findings offer valuable guidance for future research priorities in atherosclerosis and related fields.
Abstract

Keywords:
ankle-brachial indexatherosclerosisbibliometric analysis

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