Post-stroke Bone Fragility: Early Bone Loss, Risk Factors, and Recovery Considerations

Post-stroke bone fragility is marked by significant early bone mineral density (BMD) loss, especially in the limbs affected by hemiplegia. This condition is driven by reduced mobility, muscle weakness, and physiologic changes that impair bone remodeling. These skeletal changes can contribute to reduced physical function and challenges in recovery. Despite the growing recognition of these complications, screening and treatment for osteoporosis in this population remain inconsistent. Early rehabilitation strategies, including structured physical activity and pharmacologic interventions, offer potential benefits. However, gaps in clinical protocols and limited use of routine screening underscore the need for improved post-stroke bone health management. Future efforts should prioritize timely diagnosis, individualized rehabilitation, and interdisciplinary collaboration to mitigate long-term fracture risk.