Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

2.0K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
2.0K
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

513
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
513
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

33
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
33
McNemar's Test01:23

McNemar's Test

412
McNemar's Test is a nonparametric statistical test used to determine if there is a significant difference in proportions between two related groups when the outcome is binary (e.g., yes/no, success/failure). It is beneficial when we have paired data, such as pre-test/post-test designs, where the same subjects are measured under two different conditions. The test is named after the statistician Quinn McNemar, who introduced it in 1947. It is commonly used in situations where subjects are...
412

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A review of radiological characteristics and patterns of fat necrosis after different autologous breast surgery techniques.

Insights into imaging·2026
Same author

External vacuum expansion in autologous fat transfer as total breast reconstruction: Is it worth it? The interim analysis of the multicentre randomised controlled EVE trial.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Complete FLG genotyping is essential in stratification of FLG-associated disease.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

[A papula on the ankle after traveling the tropics: a case report of furuncular myiasis].

Nederlands tijdschrift voor geneeskunde·2023
Same author

Delphi survey of intercontinental experts to identify areas of consensus on the use of indocyanine green angiography for tissue perfusion assessment during plastic and reconstructive surgery.

Surgery·2022
Same author

STS pathogenic variants in a Dutch patient cohort clinically suspected for X-linked ichthyosis show genetic heterogeneity.

The British journal of dermatology·2022
Same journal

[Improving mobility in painful osteoarthritis].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The effectiveness and costs of the Back At work After Surgery (BAAS) work-integrated care pathway on return to work for patients receiving knee arthroplasty].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The rise of genetic therapies: urgent moral and societal questions].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[A man with a wound on his elbow].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[Employment of safety net enclosures].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The power of a neurodiversity perspective; demedicalizing mental health support].

Nederlands tijdschrift voor geneeskunde·2026
See all related articles

Related Experiment Video

Updated: Sep 9, 2025

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
05:06

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

397

[Single digit nail clubbing].

Nieke N P M Smeins1,2, Tim Pruimboom1, Frank S van Leersum3

  • 1Maastricht UMC+, afd. Plastische, Reconstructieve en Handchirurgie, Maastricht.

Nederlands Tijdschrift Voor Geneeskunde
|September 4, 2025
PubMed
Summary
This summary is machine-generated.

A rare subungual neurofibroma caused asymptomatic finger clubbing in a woman. Surgical removal successfully treated the condition, preserving the nail and digit.

More Related Videos

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
05:17

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy

Published on: October 27, 2015

9.0K
Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification
09:17

Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification

Published on: July 12, 2019

9.0K

Related Experiment Videos

Last Updated: Sep 9, 2025

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy
05:06

Non-Invasive Visualization of Nailbed Microvascular Morphology in Mice Using Capillaroscopy

Published on: February 28, 2025

397
A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
05:17

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy

Published on: October 27, 2015

9.0K
Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification
09:17

Adult Mouse Digit Amputation and Regeneration: A Simple Model to Investigate Mammalian Blastema Formation and Intramembranous Ossification

Published on: July 12, 2019

9.0K

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Nail disorders can present with varied etiologies.
  • Subungual tumors are uncommon causes of digital abnormalities.
  • Neurofibromas typically affect nerve tissue but can occur in various locations.

Purpose of the Study:

  • To report a case of subungual neurofibroma causing isolated digital clubbing.
  • To highlight the diagnostic approach and successful management of this rare condition.
  • To emphasize the importance of considering neoplastic causes for digital deformities.

Main Methods:

  • Clinical presentation of a 33-year-old female with a progressive nail disorder.
  • Magnetic Resonance Imaging (MRI) for subungual lesion characterization.
  • Histopathological examination of the excised tumor for definitive diagnosis.

Main Results:

  • A solitary, asymptomatic subungual neurofibroma was identified as the cause of left index finger clubbing.
  • Surgical excision of the neurofibroma was performed.
  • Complete recovery with preservation of nail and finger structure was achieved post-surgery.

Conclusions:

  • Subungual neurofibroma is a rare but treatable cause of acquired digital clubbing.
  • Multimodality diagnostic imaging and histopathology are crucial for accurate diagnosis.
  • Conservative surgical management can yield excellent functional and aesthetic outcomes.