Two concurrent nationwide healthcare-associated outbreaks of Burkholderia cepacia complex linked to product contamination, UK and Ireland, 2010-2023
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Healthcare-associated outbreaks of Burkholderia cepacia complex (Bcc) bacteria were linked to contaminated products like ultrasound gel and disinfectant wipes. Prompt investigation and product removal are crucial for patient safety.
Area Of Science
- Healthcare Epidemiology
- Infectious Disease Control
- Microbiology
Background
- The Burkholderia cepacia complex (Bcc) is a known cause of healthcare-associated infections, often linked to contaminated water-based products.
- Nosocomial outbreaks involving Bcc species (B. cepacia and B. contaminans) have been documented in the UK and Ireland.
Purpose Of The Study
- To describe two significant healthcare-associated outbreaks caused by Bcc species.
- To highlight challenges in outbreak investigation and mitigation.
- To provide recommendations for preventing future Bcc-related outbreaks.
Main Methods
- A multidisciplinary, multi-stakeholder investigation approach was employed.
- Methods included interviews, questionnaires, and targeted product sampling.
- Genomic analysis (single nucleotide polymorphism differences) was used to identify outbreak strains.
Main Results
- Two substantial outbreaks involved 153 cases of B. cepacia and 66 cases of B. contaminans.
- The B. cepacia outbreak strain was linked to contaminated ultrasound gel.
- A disinfectant wipe product was identified as the source for the B. contaminans outbreak.
Conclusions
- Investigating and mitigating Bcc outbreaks linked to contaminated products presents significant challenges.
- A low threshold for investigation, multidisciplinary collaboration, and prompt product removal are recommended.
- Interventions should focus on clinical practices and rapid response to protect patients.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
Predicting Outbreaks
Predictive analytics, a branch of statistics, uses historical data, algorithmic models, and...
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...