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Updated: Sep 9, 2025

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Keeping Water Safe in Changing Times: What Nurses Need to Know
Glenda M Payne1,2,3, Jim Curtis4,5,6
1Co-Founder and Principal of the National Dialysis Accreditation Commission and a member of the Association for the Advancement of Medical Instrumentation (AAMI) Renal Disease and Detoxification Committee.
Safe dialysis water and dialysate are critical for hemodialysis (HD) and hemodiafiltration (HDF) patients. Ensuring purity protects patients as dialysate directly contacts the bloodstream during HDF treatments.
Area of Science:
- Nephrology
- Biomedical Engineering
- Public Health
Background:
- Hemodiafiltration (HDF) is increasingly adopted in the US.
- Dialysis water and dialysate safety are paramount for patient well-being.
- Limited dedicated technical staff necessitates broader team involvement in system operation.
Purpose of the Study:
- To underscore the critical importance of safe water and dialysate in hemodialysis (HD) and hemodiafiltration (HDF).
- To review essential components and processes for ensuring safe dialysis fluid preparation.
- To emphasize the collaborative role of the care team in maintaining patient safety.
Main Methods:
- Review of water treatment system components.
- Analysis of dialysate concentrate preparation protocols.
- Examination of integrated HD/HDF system considerations.
- Discussion of essential monitoring and testing procedures.
Main Results:
- Direct infusion of dialysate in HDF heightens the need for stringent water purification.
- Current staffing models often place water system operation on direct care staff.
- Comprehensive understanding and rigorous testing are vital for preventing patient harm.
Conclusions:
- Safe water and dialysate are non-negotiable for HD and HDF patient safety.
- A multidisciplinary approach to operating and monitoring dialysis fluid systems is essential.
- Continuous vigilance and adherence to best practices safeguard patients undergoing dialysis treatments.
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