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Transcript isoform diversity defines molecular subtypes and prognosis in acute myeloid leukemia through long-read

Xiaoguang Shi1, Shuai Wang2, Shuting Yu2

  • 1Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai 200025, China; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.

Cell Reports
|September 4, 2025
PubMed
Abstract

Keywords:
CP: CancerCP: Genomicsacute myeloid leukemiaalternative splicinglong-read RNA sequencingmolecular subtypesnon-negative matrix factorizationtranscript isoform

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