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692
Concurrent Disorders and Treatment Outcomes: A Meta-Analysis.
Kathryn Danielle Scott1, Kevin Michael Gorey1
1School of Social Work, University of Windsor, Windsor, Ontario, Canada.
Journal of Dual Diagnosis
|September 4, 2025
Summary
Individuals with co-occurring mental health and substance use disorders (SUD) face worse treatment outcomes. They are twice as likely to experience relapse and related adverse events compared to those with a single disorder.
Area of Science:
- Addiction Medicine
- Psychiatry
- Public Health
Background:
- Concurrent mental health and substance use disorders (SUD) present complex treatment challenges.
- Existing research suggests potential disparities in treatment effectiveness for individuals with dual diagnoses.
Purpose of the Study:
- To investigate if individuals with concurrent mental health and SUD respond less favorably to treatments compared to those with single disorders.
- To examine if vulnerable groups (women, racial minorities, low-income individuals) experience further disadvantages in treatment.
Main Methods:
- A rapid review and meta-analysis approach was employed.
- Data synthesized from 35 systematic reviews and meta-analyses (2000-2024) and 13 primary studies (2020-2024).
Main Results:
- A pooled risk ratio of 1.71 indicated that individuals with concurrent disorders are significantly disadvantaged in treatment.
- No evidence was found to support or refute moderating effects of gender, race, or income on treatment outcomes.
Conclusions:
- People with concurrent mental health and SUD are twice as likely to experience negative outcomes like relapse, ED visits, and rehospitalization.
- Further research is needed to understand treatment disparities in vulnerable populations.
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