[Dexamethasone - Risk Factor for Wound Healing Disorder and Hyperglycaemia?]

Area of Science:

• Anesthesiology
• Pharmacology
• Surgical Care

Background:

• Postoperative nausea and vomiting (PONV) are common complications.
• Pain management and reduced hospital stays are key goals in surgical recovery.
• Wound healing and glycemic control are critical considerations for surgical patients.

Purpose of the Study:

• To evaluate the efficacy of a single 8 mg dexamethasone dose in reducing postoperative complications.
• To assess the safety of perioperative dexamethasone in patients with well-controlled diabetes mellitus.
• To determine the impact of dexamethasone on wound healing and blood glucose levels.

Main Methods:

• Prospective study design.
• Single administration of 8 mg dexamethasone during surgery.
• Monitoring of postoperative nausea, pain scores, hospital duration, wound healing, and blood glucose levels.

Main Results:

• Dexamethasone significantly reduced postoperative nausea, pain, and length of hospitalization.
• No increased risk of wound healing disorders was observed.
• Patients with well-controlled diabetes showed a slight, clinically insignificant increase in blood sugar levels.

Conclusions:

• Single-dose perioperative dexamethasone is a safe and effective option for managing postoperative outcomes.
• This intervention improves patient recovery without compromising wound integrity.
• Dexamethasone can be safely used in diabetic patients undergoing surgery, with careful glycemic monitoring.