Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Metal-Ligand Bonds02:51

Metal-Ligand Bonds

21.5K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
21.5K
Network Covalent Solids02:18

Network Covalent Solids

14.5K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
14.5K
Protein Networks02:26

Protein Networks

4.1K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.1K
Protein-protein Interfaces02:04

Protein-protein Interfaces

13.2K
Many proteins form complexes to carry out their functions, making protein-protein interactions (PPIs) essential for an organism's survival. Most PPIs are stabilized by numerous weak noncovalent chemical forces. The physical shape of the interfaces determines the way two proteins interact. Many globular proteins have closely-matching shapes on their surfaces, which form a large number of weak bonds. Additionally, many PPIs occur between two helices or between a surface cleft and a...
13.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Metabolic Syndrome Predicts Chemotherapy Resistance and Poor Prognosis in Epithelial Ovarian Cancer: A Retrospective Observational Cohort Study.

International journal of women's health·2026
Same author

Extracellular Vesicle-Associated Non-Coding RNAs in Preeclampsia: Mechanistic Insights, Biomarker Discovery, and Emerging Nanomedicine Concepts.

International journal of nanomedicine·2026
Same author

Isolation and reactivity of an alkyl-substituted germanium(I) radical anion.

Nature communications·2026
Same author

Theoretical Modeling of the Self-Assembly of Low-Dimensional Superstructures With Exposed Nitrogen Coordination Centers.

Chemphyschem : a European journal of chemical physics and physical chemistry·2026
Same author

Natural killer cell dysregulation in polycystic ovary syndrome: immunometabolic and reproductive implication.

Frontiers in immunology·2026
Same author

A dual-mode large language model assistant for on-surface reactions <i>via</i> fine-tuning and retrieval-augmented generation.

Chemical science·2026

Related Experiment Video

Updated: Sep 9, 2025

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry
08:18

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

1.8K

Constructing High-Entropy Molecular Networks on Metal Surfaces.

Jiayi Lu1, Xinyi Zhang1, Damian Nieckarz2

  • 1Materials Genome Institute, Shanghai University, 200444 Shanghai, China.

Journal of the American Chemical Society
|September 4, 2025
PubMed
Summary

Researchers explored creating high-entropy molecular networks on metal surfaces. They found that molecular shape and functional groups significantly influence the network

More Related Videos

Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.3K
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

3.1K

Related Experiment Videos

Last Updated: Sep 9, 2025

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry
08:18

Microscopic Visualization of Porous Nanographenes Synthesized through a Combination of Solution and On-Surface Chemistry

Published on: March 4, 2021

1.8K
Synthesis and Characterization of Functionalized Metal-organic Frameworks
11:27

Synthesis and Characterization of Functionalized Metal-organic Frameworks

Published on: September 5, 2014

48.3K
Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers
07:14

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

3.1K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Surface Science

Background:

  • High-entropy materials (HEMs) exhibit unique properties due to compositional complexity, with applications in catalysis and energy storage.
  • Traditional HEM research focuses on metal alloys, leaving organic high-entropy systems underexplored.
  • On-surface chemistry offers a platform for constructing complex molecular architectures.

Purpose of the Study:

  • To investigate the construction of high-entropy molecular networks on metal surfaces.
  • To explore the role of molecular design (shape, functional groups) in achieving high entropy in 2D molecular systems.
  • To understand the formation mechanisms and factors influencing mixed entropy in these novel materials.

Main Methods:

  • On-surface synthesis using pyridyl-functionalized ligands with varied aromatic backbones.
  • High-throughput sample preparation via a Venn diagram-inspired mask.
  • Real-space characterization using Scanning Tunneling Microscopy (STM).
  • Computational modeling using Monte Carlo and Molecular Dynamics simulations.

Main Results:

  • Successfully constructed 2D molecular networks stabilized by metal coordination.
  • Identified molecular shape and the number of functional centers as critical factors for promoting mixed entropy.
  • Observed both ordered and disordered network assemblies, demonstrating control over entropy.
  • Simulations elucidated formation mechanisms and entropy-influencing factors.

Conclusions:

  • Molecular species significantly influence disorder and stability in high-entropy molecular networks.
  • This work advances the understanding and construction of low-dimensional high-entropy molecular systems.
  • Paves the way for designing novel functional materials based on high-entropy principles in organic systems.