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Updated: Sep 9, 2025

Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
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MYC-Driven Activation of USP39 Enhances SRSF1 Stability and Promotes PDAC Progression

Benteng Ma, Alexander J Kral, Xin Zhang

    Biorxiv : the Preprint Server for Biology
    |September 5, 2025
    PubMed
    Summary

    Researchers discovered a new regulatory pathway in pancreatic cancer involving MYC, USP39, and SRSF1. This axis stabilizes key proteins, promoting tumor growth and offering a potential new therapeutic target for pancreatic ductal adenocarcinoma.

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