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Separating Biological Variance from Noise by Applying Expectation-Maximization Algorithm to Modified General Linear

Tien-Wen Lee1

  • 1The NeuroCognitive Institute (NCI) Clinical Research Foundation, Mount Arlington, New Jersey, USA.

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology
|September 5, 2025
PubMed
Abstract

Keywords:
design matrixexpectation–maximization algorithmgeneral linear modelglobal optimumlocal optimum

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